Perhaps the curve of familiarity with the other for any empiricist.
Look at a totally foreign thing. First comes cautiousness about whether it exists, but then just by looking you get a vague notion that it's a coherent thing. Then curiosity draws you closer to it and therefore you see the thing in greater detail. Some of the newly visible bits mess with your idealised picture of the thing from before. Only if you decide to persevere in understanding this other do you start to integrate these discordant stimuli into the currently running model of it. As the thing comes into clearer focus you realise that the discoveries are slowly revealing negative entropy. It's safe there. Following the trail inevitably results in reaching the end of it.
If only there were a standardised protocol for consuming the universe.