Ask HN: Who has the best chance to “10x” the human mind?

Peter Thiel, Tim Ferriss, etc. have been talking a lot recently about incremental improvements vs. "10x" improvements. I'm personally most interested in the human mind and therefore curious if there are any companies or organizations with the potential to take a such a leap with the capacity of the human mind. Of course there is the BRAIN program, but I'm looking for startups/consumer-level "moonshots" with the possibility to change how we think/operate.

*I've intentionally left my question a touch vague to keep the conversation open.