The interface and workflows are simple, yet extremely powerful if you spend some time understanding the tool. I have used Inkscape exclusively to do all my interface design work during my career.
After moving to OSX, I was put off by the lack of native support. So I tried moving to Sketch and Illustrator. I found Illustrator to be overly complicated and plain bloated. I've always had a distaste for Adobe software and Illustrator maintains that negative image for me. Sketch on the other hand was unstable when I tried it. It had some serious bugs that made it unusable.
I went back to Inkscape and am now used to the GTK quirks & the lack of Retina support. The software itself remains my favorite tool. And I'm excited to see this major update to Inkscape.