Are you sure?

http://www.paulgraham.com/avg.html

Technology always matters.

Luckily you have already picked one of the best available: .NET ecosystem.

Also:

"And if you’re not building something completely new and patentable not a single of your (potential) investors will ever care about the latest fancy JavaScript framework, database, or programming language you’re using."

How about Unity3D? Not new, not patentable, but Mono and C# was an ideal choice. It mattered to them, it mattered to investors.