Akamai, the CDN used by Facebook went down before Facebook for me this morning: http://www.downforeveryoneorjustme.com/akamaihd.net
Was using both when they became unresponsive, resetting routers all over the shop.
http://www.akamai.com/html/customers/customer_list.html
I wonder what makes FB and Instagram different?
Honestly, I doubt it was an Akamai issue. If Akamai experienced network problems, dozens or hundreds of sites would be affected. If an Akamai config issue (ie human error) were to blame, then it would probably only affect one site, not several. Neither FB nor Akamai is dumb enough to push multiple site changes at once.