I wish for this as well. When I was younger, I often used asm blocks in my C code to implement things like blitters. You could even use a variable name as a source/destination in instructions and the compiler did the right thing!
https://gcc.gnu.org/onlinedocs/gcc/Extended-Asm.html
So today we should be able to write 90% of an app in a rapid application development (RAD) language like HyperTalk, MATLAB or Python (or my favorite, the language that doesn't exist that combines all of these) and micro-optimize in places that need it using C/Java/Go/Rust etc. The compiler should automatically generate all glue code for variables and function calls.
My sense of this is that functional programming is gaining popularity because most people are working a few levels too low to be productive. Short imperative code should be able to act as a black box with no access to global variables or sockets and be exercised with known inputs/outputs and be represented in a functional manner. I wish we could deal with logic as truth tables and state transitions rather than the code (declarative rather than imperative).