Mind I recommend earplugs if you want absolute quietness? Sometimes I do wear headphones on without anything playing, because they provide really good sound isolation. You could get specifically noise-canceling headphones for that.

Regarding getting asked all the time by other people, I would think that is more of an organization problem. Nothing stops me from pinging coworkers on irc or any other IM program for help or actually going to their office in person. As an advantage to openspace office, I can just raise my head, look at my coworker and ask "hey, do you have a second?". More often than not I get a "sure, give me a few minutes" if they are busy or they can just lean over or walk to my desk without wasting too much time. And if it's a more serious issue it's "Shall we move to a more private place?".

I honestly don't see a problem, nobody stops you from telling your coworkers to check the documentation regarding their question (if there is one, is it a common question? Maybe you should write something up since you are more knowledgeable on the matter and don't like being interrupted about it). But yeah, this is probably because I'm just an intern and I don't have experience on the matter, but I enjoy working like this.