What other things? Did you run FSecure, Panda, ESET, Emsisoft, Avira, Avast, Herdprotect? It might be useful, but it is dangerous. It should be an absolute last ditch effort, not standard procedure.
>AdwCleaner requires a restart to finish up, as I understand it.
Try running it twice in a row without a restart. Try running it before and after a malwarebytes scan, without a restart. Does it find things?
>technical clients (say, 1 in 10) are more willing to explore SSD and appropriate RAM.
Thats why you word it "would you like me to make your computer much faster for $100 dollars. I can replace the moving parts with electrical ones."