I think zzzcpan is suggesting to compile from the new toy language to C and then use a C compiler to get native code. This doesn't preclude only using libraries written in the new language. CHICKEN is a Scheme compiler that takes this approach.[0]
The submitted essay addresses the problems that can result from this sort of compilation style with the question "Will native compilation of a big project result in so much code that there's a global slowdown (something actually true of mid-1990s Erlang to C translators)?"