In short, auto-start audio in ads is quite simply so far outside of what I consider acceptable behavior, that I'm willing to burn the whole goddamned business model to the ground to stop it. I disable AdBlock Plus for sites that I know to behave responsibly with regard to their ads (reddit, probably a couple of others). If there were a list of Advertising Good Citizens who never use auto-starting audio ads (such a list would probably need to demand a few other things, like a good privacy policy, no popups/popunders, etc., but audio is the single reason I installed AdBlock Plus), that could be dropped into AdBlock Plus, I would happily use it. I don't mind ads, but the second somebody disrupts my work, my conversation on Skype, my partner's sleep, my music listening, etc. is the second I grow to hate the site and the advertiser.