This is essentially the problem that I have with the Drake equation. It encourages--whether that's the intent or not--taking a reasonably known and very, very large number (number of stars) and multiplying it by probabilities/percentages, some of which (we think) we know with at least order of magnitude accuracy. But others we have absolutely no idea. And saying some of those events (such as the evolution of intelligence as we understand the term) has a 1 in a billion probability of occurring SOUNDS like a worst case for-the-purposes-of-argument plug-in. But it's really not.