I traveled around India for around 4 months last year and came across the same debilitating poverty that you mentioned. Men missing legs dragging themselves forward on dollies around Lajpat Nagar market, teenage mothers panhandling with multiple kids at chaotic intersections, rows and rows homeless people sleeping outside. My coping mechanisms improved, but I wouldn't say I became indifferent to it. Seeing the poor without being able to help feels to me like pain without purpose. So after a while I learned to look away from the poverty for my own sanity. Can this lead to indifference? Yes. Does it have to? I hope not. I hope that one day I will have the resources to turn my gaze towards poverty again and feel less helpless.