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The ending of the interview is really disturbing:

Is there a lifetime ahead for a 34 year old writer who’s just delivered a thousand page bomb on us?

David Foster Wallace:

I think assuming I drive carefully, sure.

Christopher Lydon:

Please do.

Listen to the end of the Charlie Rose interview. Last words something about not jumping off a building any time soon.

Nothing disturbing about these things. Depressed people think about that a lot and blurt it out on occasion.