Pixel Qi had some pretty interesting products being developed including reflective LCD displays. I am not sure how readable they are in low light conditions, but I always thought it would be cool to have one of these for programming.
Pixel Qis are not e-ink but still amazing. As you said they are reflective LCD, and can also be backlit, thus readable in low light just like a regular LCD. Their market is also small devices, so the size problem is still there (Last time I checked I think there max size was 10.1 inches)