The Amiga was initially used to create the effects for Babylon 5.

https://www.youtube.com/watch?v=seznQmDp2pU

http://www.midwinter.com/lurk/making/effects.html

http://www.geek.com/games/cgi-first-introduced-to-tv-in-baby...

I thought JJ Abrams mentioned that he used the Amiga for something in the 1990's but I can't find anything in Google.