This has essentially happened already. Comedy central censors South Park in a direct response to threats made against them regarding depictions of Mohammed.
"Steve Carell’s North Korea Movie ‘Pyongyang’ Canceled in Wake of Sony Hack" http://www.thewrap.com/steve-carells-north-korea-movie-pyong...
Would he have dared to make a comedy mocking Mohammed the warlord turned prophet and 72 virgins in heaven? I guess he was smart enough to figure out that life under police protection would have cramped his partying.
Oh, and Seth is a total prima-donna, witness his recent tirade against Cathay Pacific because they wouldn't allow his wife's dog onto the plane due to the breed being more susceptible to death during flight.