As someone who has been using a Kindle for almost all my book reading in the last few years, the major publishers don't care. Doesn't matter what I read it tends to have quite a few OCR errors and other mistakes that clearly exist for the print edition (extra hyphens) or 'correcting' things that used to be hyphenated (by removing the hyphen that needs to be there).

My new Kindle has the ability to let me report typos and other content errors.

I've been using that feature A LOT. I've reported 13 content errors in the last month, and I'm not reading all that much, just a few hundred pages in that time.