Human bodies :
* require a constant supply of oxygen. Which is available effectively nowhere except deep inside gravity wells.
* require a constant supply of water. Which is available effectively nowhere. H may be everywhere, but O is nowhere convenient.
* require G-forces to be between 0.8 and 1.2 for long term survival. Can tolerate very brief exposure up to about 4G. This means the vast majority of planets are effectively uninhabitable just for that reason. And harshly limits the maneuvers possible to get there.
* require a sun-like source of radiative energy with a certain minimum intensity (one of the reasons people can't survive on Mars without additional UV exposure)
* require the presence, in small quantities, of half the elements with an atomic number up to 26, and several found further on. H, C, N, O, Na, Mg, Al, S, Cl, K, Ca, Fe, and I. Some of these are not very common, and they may be very hard to find. Not finding them first means it becomes impossible to have kids, increased occurrence of things like cancer, and a few years later it becomes lethal.
* require gravity. Which is massively inconvenient for operating ... well, anything really
* require radiation shielding against solar radiation for long term survival that requires about a hundred kilometers of atmosphere or several inches of metal (if you're to survive long term, for short excursions less isolation can be acceptable, also in Low Earth Orbit (like ISS) you're still partially shielded by the earth)
* require radiation shielding for charged particles that is provided by the earth's magnetic field, but requires metal barriers in outside of those fields
* require the sun's plasma barrier around the solar system to weaken interstellar background radiation to the point that the earth's atmosphere/reasonable thickness metal can actually stop it.
* require to be inside the galaxy, again to weaken certain types of radiation
* require a minimum distance to any supernova explosion of around 50 light years to survive (or yet more shielding)
* require to be in groups of at least 50 for long term survival (or we won't have enough gene variation and die off over time), even though short excursions can use a limited number of people. This is the low end of the estimates.
* require to be in groups of 2-3 people at least even for short term excursions or there will be severe psychological consequences
* require the presence of large masses of bacteria to fulfill certain bodily functions the human body can't actually do itself (best - but not only - example being digestion)
* require the presence of bacteria outside of the body to create compounds that we can't make ourselves. Some of these cannot be stored for any length of time, you need to take bacterial colonies or, better yet, plants + bacterial colonies with you and let them grow.
This isn't a complete list by any means. Human bodies will never go very far from Earth.