Until I upgraded to Snow Leopard, I was using fink with the unstable binary packages: http://finkers.wordpress.com/2009/06/01/fink-and-binary-dist...

I could use apt and dpkg, it did't build the world whenever I wanted a package (cough Macports), and since it just used binaries, installs were super-fast.

Last I checked, fink wasn't all that usable with Snow Leopard, but it's by far the easiest package management method for Leopard.