The top 10 cities in the US by GDP are, in order:
* New York
* Los Angeles
* Chicago
* Washington D.C.
* Houston
* Dallas
* Philadelphia
* San Francisco
* Boston
* Atlanta
Here, for your reading pleasure, are the ground travel distances between all of those cities:
New York
Los Angeles 2475
Chicago 790
Washington D.C. 226 **
Houston 1416
Dallas 1389
Philadelphia 94 **
San Francisco 2907
Boston 215 **
Atlanta 750
Los Angeles
Chicago 1745
Washington D.C. 2288
Houston 1379
Dallas 1235
Philadelphia 2401
San Francisco 380
Boston 2611
Atlanta 1947
Chicago
Washington D.C. 696
Houston 1083
Dallas 924
Philadelphia 759
San Francisco 2130
Boston 983
Atlanta 716
Washington D.C.
Houston 1400
Dallas 1328
Philadelphia 136 **
San Francisco 2816
Boston 437 **
Atlanta 639
Houston
Dallas 239
Philadelphia 1544
San Francisco 1927
Boston 1848
Atlanta 792
Dallas
Philadelphia 1464
San Francisco 1726
Boston 1791
Atlanta 781
Philadelphia
San Francisco 2876
Boston 307 **
Atlanta 783
San Francisco
Boston 3099
Atlanta 2472
Boston
Atlanta 1099
I have, I hope helpfully, starred the sub-700-mile routes that are already served by the Acela.The average ground distance between these cities is (wait for it) 1,356 miles.
Later
You edited your comment upthread to include specific routes.
My response --- apart from wondering why taxpayers in Arizona should fund a rail linkage to Orlando, the 30th biggest economy in the country, to Tampa, the 27th --- is to suggest that adding Florida to this graph would not improve the average cost of the edges.