It's a curse, in a way, to have (be?) a brain trained to recognize and solve problems, optimize expected outcome, and see through bullshit when the popular solution to existential debilitating dread — religion — crumbles at the slightest analysis. Ignorance is bliss, to add to Puchner's ostensibly empty bromides.
There are a lot of very intelligent people who believe in an afterlife. They aren't ignorant about the reality of death, nor are they practicing "bullshit". They honestly and earnestly believe in what they advocate.The disagreement is fundamental in nature. The afterlife was never demonstrated to be false. It was rejected because it contradicts naturalism. Believers didn't make some mistake in logic along the way, they started from a different set of assumptions.
To rephrase your original statement:
It's a curse, in a way, to have (be?) a brain trained in logical positivism, to only accept scientific answers, and reject out-of-hand any other possible answers which might provide hope rather than existential debilitating dread