The engineering reason to upsample is to simplify the analog anti-aliasing filter on the other side of the conversion by giving it a wider transition band to work with. It also means one analog filter can handle a wide range of samplerates.
masklinn is right though—from a consumer perspective, there's no real reason to care how the conversion's done. Hopefully your DAC was designed by a team that knows what they're doing and will handle whatever rate you feed it.
Of course, if you have one of those obnoxious devices that can't actually clock below 48kHz or a mixing daemon configured to run at 48kHz, you're stuck oversampling anyway, and depending on your environment that might be done anywhere between amazingly well and linear interpolation. Many years ago I was stuck playing that game on Linux—in that case, there's an audible benefit from using a better designed upsampler in your player.
But if you're equipment's not broken, it's a waste of CPU cycles.