Sharing a single scoping system between JS, HTML and CSS removes the need for global symbols (classnames or ids) to link the two together.
Abstractions in preprocessors are implemented by means of macros, and can lead to large file sizes.
Proper usage of CSS preprocessors will result in much the same code that this tool will generate. Because in the end they both generate the same CSS.
Although it's not necessarily the main way the author is suggesting interacting with this library, it can be used as a tool to apply inline styles directly to elements, which gives you total control over the scope of your styles.
As I said elsewhere, if this were a system done on the back-end (or even in something like Grunt) so that it was part of a compiling process then it would have merit. But from what I'm seeing this appears to run only on the client side which I feel is a bad idea.
However, you're wrong that classnames and ids are always necessary. You can set the HTML "style" attribute directly when generating the view.
There are several different ways to handle CSS and each has their own pros and cons. But I'm assuming you're talking inline styles on the HTML elements directly? If so, while useful and I do it myself often, it is not optimum. If you're talking about injecting the styles on or before page load for that particular view, of course you can; but that doesn't mean anything different than what I've been saying at all. In the end it is still CSS and if it doesn't done properly in the beginning it will eventually cause problems.
It doesn't help that in most of the examples the Javascript implementation is more complex than the css implementation.
I agree on the complexity issue with the examples, I don't see how the 30% savings claim would hold up.
Preprocessors will generate bloated CSS if not coded properly, same as it's possible to hand-code bloated CSS.
There are libraries that generate vendor prefixes at run time. If prefixes are really a bother (they're not as much anymore) then preprocessors and other compiling tools have solutions for that as well. Which will be more efficient for the browser.
2. I know code reuse technics in css, they are mentioned in the presentation. Cascades do not work for component based development. Adding multiple classes to an element leads to awkward code and also will lead to namespace conflicts if you don't name everything very specifically.
3. Vendor prefixes are there and will be used for new features too. They will not go away. Precompilers can't avoid generating all prefixed variants.