Find a job that allows telecommuting as an employee or contractor. You can also start your own business from home if you cannot find a job. Depending on what you have to offer employers you can be rewarded very handsomely, maybe even make more than an at the office employee plus you save money and time by not having to drive to and from an office.
If you start your own business from home you can make some serious money and save a large amount on expenses that are commuter related (driving to and from work, gas, car maintenance, stress, less laundry, etc.).
Is there anything specific that you were wondering about doing from home?