Oddly enough, I found the 10x10 easier to solve then the 6x6 and the 8x8. After a couple play-throughs I think I know why. When trying to determine your next move, there's 3 options.
1. Look for a chance to play a block that wouldn't cause a chain of 3 colors together.
2. Look so see if the row or column has enough of a certain color in it.
3. Look to see if the row or column is a duplicate of another.
1 and 2 are easier to spot, but 3 is actually quite difficult and takes a lot of time to determine. On the 10x10, option 3 is almost never the determining case, probably because there are so many more possible configurations for a row or column, vs on a 6x6.