Ask HN: Advice on moving for a job

I graduated in May with a BS in CS of and immediately landed a job doing PHP work in a really small startup in my hometown in NE Pennsylvania. I'm really looking to spread my wings and move to some place to work at a great company so I can get more experience and progress as a developer. The problem that I'm having is that the places that I really want to move are pretty sparse as far as tech goes (Portsmouth, NH and Portland, ME), and I have no idea where else to even look.

I was wondering if any of you have any advice on good places in the US that have a decent amount of opportunities for tech, but are still really great places to live. I was also hoping to hear some stories from people who picked up and left to pursue bigger and better things.