Supply curves are overwhelmingly determined by the marginal cost of production. Fixed costs and barriers to entry help determine the number of supplier firms trading in the market.
The suppliers do not know, a priori, the tastes of buyers and the shape of the demand curve. They only know that they can stay in business as long as their marginal cost per unit is less than the sale price on the open market. You don't know whether 500 people will buy at $2 or 50000 people will.
That $1000 is the entry ticket to the market. If the supplier produces just one unit, it is already paid and gone. As they say, sunk costs are sunk. That up-front cost is not recoverable through per-unit sales. (It is possibly recoverable through the sale of the business or its capital.)
So with respect to your example, the seller pays $1000, sells 501 units at $2, then sells the business assets while exiting the market. The buyer and seller benefit to trade is entirely unaffected.
The total amount buyers would pay is $1800. The total cost to sellers for a cleared market is $501. That makes a potential total benefit to trade for a cleared market of $1299. But the market clearing price only allows the seller to capture $501 of that benefit.
The seller probably does not know those exact numbers beforehand, and cannot use them to conclusively justify the $1000 investment. How does the seller know that one buyer is delusional enough to pay up to $800 for an item that costs $1 to make? If he does know, he simply charges that person that price and removes him from the equations. Then you're still stuck needing to know the next most demanding buyer, and how much they would spend. Each party has imperfect knowledge of the market, and there is no way for any one of them to make decisions based on knowing everything.