I discovered that I could listen to This American Life while playing Borderlands (and its sequels). The game doesn't have characters that talk to you nonstop (especially when you are playing side missions) and something about the shoot-y gameplay meshes extremely well with talk radio.

The weird part is that the two mediums got completely and inseparably tangled together in my memory. When I think of a specific This American Life episode I can instantly recall the 3d layout of the level that I happened to be exploring while listening to the episode. And when backtracking later in the game I see the terrain features and the ideas and important parts of the show flood back into my mind.

I find it very strange, and very interesting, too.