The whole directory is inside a Truecrypt disk, btw (but I am running Crashplan after mounting the Truecrypt volume, so for Crashplan the files are visible).
I did a few (say half a dozen in the last 3-years) restores of a specific file and I did a full restore of the whole directory to a completely different machine (a Mac) due to problems with my old laptop - they replaced the HD and I had to keep working for a couple of days before getting it back.
And another full restore when they finally replaced the laptop with a new one.
In all these cases it worked without a hitch.
I also played a bit with their "backup to a friend's computer" thing, but haven't tested it in depth. Never used their online version, though, so I can't say anything about that.
I was restoring them from Crashplan backups on my Synology though, the Crashplan servers can be kinda slow at times (in range of 10-30Mbit/s transfers).
No idea if this is expected (their account is a free one, where you cannot change many of the retention and backup settings) or it's a bug, but this made me check the cloud backup also and compare the files on the disk with the recovered ones. No problems so far, but I only managed 1TB (of 2.5TB backed up).