You know what's really cool about this? Microsoft and Apple have both taken stabs at this problem multiple times. The companies that make the operating systems on about 99% of PCs have both tried this. They've had some success at it, but it's never been a killer app or a feature that people rave about.
Knowing that, dhouston still created DropBox. He did a fantastic job. He knocked it out of the park. Now 2 million people have used the thing and he's well on his way to building a very successful business with it.
Don't let the big guys scare you.