It's extremely difficult to imagine a world in which distributed, unspecialized manufacturing is actually a reasonable way for most people to get their goods.
One argument many people have made is look at the personal computing revolution, shouldn't we see the same thing in physical manufacturing?
And the answer is: yes, we will the same thing. But look at what is actually happening: you have a brief 20-30 year period in which distributed personal computing actually happens, but then once the internet comes about things have slowly started migrating back to centralization and specialization (ie: Facebook instead of distributed social networking).
I expect the same will happen with 3d printing. Sure, 3d printing might be the best way to print that obscure part you need for an old car. But for every day items? Unlikely that the efficiency gain made by getting rid of shipping is actually offset by printing something in your house on demand.
I think it'll work out like on-demand printing. That laser printer in your office is fine for printing out a one-off contract. But when the time comes to restock your company's collection of brochures, it's probably best to send out to have them printed on high-volume equipment that can do a better job of it.
Clothing sizes today are a messy approximation of what people actually want. It's a compromise between the ROI possible in a mass-production, mass-transport world, and the perfect fit.
News and music used to be produced and distributed like clothes--centralized production of a limited number of product options, which are then shipped to lots of people. Today people can completely customize their news and music consumption through a wide variety of dynamically personalized channels.
Personal manufacturing can do the same thing for tangible goods. But the current "3D printing" technology, which is extremely limited in terms of materials, size, durability, etc.
Even if you go full science fiction and have a machine that perfectly rearranges the atoms and you can buy specific atoms (a la Diamond Age), the guy who has a deal on bulk atoms needed to make a shirt will make it cheaper than you will make it in your kitchen on your maker.
Maersk's (and other similar companies') big idea was that if you put things in regularly sized containers, you can a) Calculate space very easily and use space efficiently b) Not worry about packing things at the dock and let the customer best pack the thing as opposed to you wasting time on it c) Use the same container to move the goods across ground too d)Reuse the container. So this was kinda IKEA flat packing before IKEA existed.
It really is hard to beat the economies of scale here - even the largest cargo planes move laughably small amounts compared to these things. Drones? No way.
Drone, I think, could disrupt something else, which is house delivery. Small weight, short distance. That's what it'd be good at.
[0] http://richardtorian.blogspot.com/2012/01/cost-per-ton-mile-...
http://www.amazon.com/Race-Against-Machine-Accelerating-Prod...
If you want to disrupt this industry, a completely different mode of transport would have to be invented. Good luck building your teleporters or your ocean-length, frictionless rail lines, everyone!
That said, "Tea, earl gray, hot."....someday.