There's a literature on burnout. Burnout is the qualitative word for stress induced sterility -- ie "Things are so bad that having a child right now would be disastrous"

(ie people reporting burnout are usually temporarily sterile, people who are "stressed but happy" are usually not sterile)

This is why burnout correlates so strongly with being overworked. Your body is rightly concluding it can't reproduce in your current situation, and gives you a strong prod toward fixing the problem.

Apparently Marissa's "resentful meter" correlates strongly with her body's "I can't reproduce in this situation meter". I don't think this is true for most people.