That said, this kind of formal, mathematical approach to evolution is becoming increasingly powerful, and it's worth speculating if there might not be a provable theorem connecting random DNA variation and the laws of probability at the molecular level with the fact of macroscopic evolutionary change, speciation, etc... something like Boltzmann's H-theorem in thermodynamics, which attempts to show how micro-physics (kinetic theory) can be used to prove the macroscopic 2nd Law of Thermodynamics.
This would make evolution not a theory but a theorem, which I call "Darwin's Theorem". I've played around with the math a bit (I'm a physicist, not a mathematician) without getting anywhere, and wrote a what-if novel about the possibility (it plays with even more speculative ideas as well), in part with the thought of popularizing the idea, because I think it's worth people thinking about: http://www.amazon.com/Darwins-Theorem-TJ-Radcliffe-ebook/dp/...