Say you're using your computer 12 hours a day, half of that doing tasks where memory usage greatly exceeds your physical memory, and you're using 1/4 of the bandwidth of the drive to swap in/out (of which 1/2 are writes).
Under this quite heavy scenario, the writes will catch up to this endurance test after 32 years.
The speed, price & capacity of these drives are (at least for now) improving so quickly that by the time you wear one out, even with torturous use, replacing it will be trivial.
Cost per gigabyte has halved over the period of this test. So even when taking the drive that just died and using it for the most pathological use case imaginable, you'd be buying a $200 drive today, replacing it with a $100 drive in one year, $50 in two years, etc. Not a big deal.
I can get back to you in a little more than a year about the 750 "GB" Samsung 840 EVO in the lady's laptop, and 6->8 months on the Crucial M4 SSD in my gaming PC. :)
But as it turns out OS X behaves really badly if you try to take away its swap (last time I tried, the kernel memory usage slowly increased until it consumed almost all memory; I re-enabled flash and rebooted and it got back to normal. It's a bit annoying that we've become so dependent on a kludge to work around too little memory. (Brings me back to my Amiga days and the long, heated discussions about whether or not swap was a good idea in the first place)
sysctl -w vm.swappiness=0
to make permanent, set vm.swappiness=0 in /etc/sysctl.conf
Though for a desktop machine, disabling swap probably won't help improve performance
post 3.5 it does actually hard-disable, but setting swappiness to 1 gives the same behaviour as swappiness=0 in < 3.5