A one-man experiment in anti-aging

Particularly because that's the only evidence he's collecting to show that his experiments -- lots & lots of concurrent experiments that he's continually changing for murky reasons -- are working.

He just... says stuff like this:

> At first I expected to be able to set back my telomere clock by up to 8 or 9 years per year, but subsequently revised this to about 5.1 years per year.

> The astragalus extract actually finally turned out to work rather better, in fact, than TA-65.

...with no explanation at all. He's clearly learned some domain-specific vocabulary, but spending all of his money on supplements rather than any kind of testing whatsoever, or even taking the time to work out a more scientific approach.

I don't see how his "experiments" have any scientific value beyond "here's a guy who ate (or rubbed into his scalp, or whatever) X quantity of Y every day for a few months or years, and it didn't seem to do him any serious harm".

Edit: saying "whatsoever" 3 times is overkill...

Agreed. Couple of blurry photos (especially second one, from 2013), plus angle in which second photo is taken is very misleading - people can look younger or older just by changing angle. Good, no-BS article must have 2 clear, crisp, hi-res frontal photos for fair comparison, together with EXIF info (yes, I know it can be faked but still...). Furthermore, on first photo he is frowned, on second he is smiling which is another suspicious point. All in all, to me it looks like this story has got no substance.

looking at his avatar - I'm not sure he's sharing the truth. If you're running all of these cutting edge anti aging experiments surely can upload a non pixelated photo?

Yes, self-experimentation and knowingly risking the most precious thing there is - your own life, to advance science and help others, is one of the most heroic things. I'm not sure if Jim is doing anything as heroic and with the same admirable motives, but I really hope he's and other self-experimenters contribute to medicine and science, because really the pace, cost, and the moral concerns of studies slow progress down tremendously.

Why is the quality of photos he takes of himself also like they were taken in the 90's.

How old is he?

I never really understood the overall hypothetical effect of this approach. What I find interesting that his regimen does not have any mitochondrial enhancers (outside of the standard Co-Q10), which is something most anti-aging programs today focus on, specifically, PQQ, which generates new mitochondria.