As I said in my comment,
>Guile can run elisp already
Guile already interprets Elisp.
Elisp can run unmodified on Guile.
Guile, the virtual machine, contains a front-end for Emacs Lisp.
المكر ينفذ أصلا إيماكس اللثغة.
Guile jatorriz exekutatzen emacs Lisp.
It is true there are no compatibility issues because Guile is an implementation of Emacs Lisp.