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https://github.com/jerrymarino/cupertinojs

Cupertino.js already supports this. It's currently pre-alpha, but there's a JavaScript iOS app that works in the simulator.

Nimblekit[1] uses HTML + JavaScript - is that any good for you?

Edit: guh, just spotted the Sencha acquisition note, might be a dead-end.

[1] http://www.nimblekit.com/

https://github.com/trueinteractions/tint2

This has the goal of eventually letting you do just that. I'm personally very excited over it!

http://ionicframework.com/

AngularJS + Cordova Framework for building hybrid apps

Ionic is amazing. I started using it last night.

PhoneGap by itself is too much of a blank canvas. This framework is opinionated and you can get something sophisticated up and running fairly quickly.

Have you not come across Appcelerator/Titanium?

agreed, this JS support almost raises JS to first class status on osx. wish the same could be done for ios.

using cordova and similar is okaay, but not nearly as elegant as just writing the app in JS due to the tools required.

i use pythonista on my ipad. -- pretty amazing, cwoukd love the same for js/node on ios