From what I've observed, quite a few people on HN have read "On Intelligence" and are receptive to these type of posts.

I'm guessing this is the same Scott that gave the presentation at OsCon? I wasn't physically there, but watched it online. It was one of my early exposures to NuPic, CLA, HTM, Jeff Hawkins, etc. Thanks for that.

Have you had a chance to play around with NuStudio (by David Ragazzi)? I don't think I've seen you comment on it via the mailing list.