They don't spam me, their DNS service is rock-solid, and their website (while a bit lacking in the graphical design department) is fast, clean, and ad-free. I also get clear, to-the-point reminders when a domain is up for renewal.
I have dozens (not hundreds or thousands) of domains registered, but I would recommend them without hesitation to anyone looking for developer-friendly registration and hosted DNS.
http://docs.aws.amazon.com/Route53/latest/DeveloperGuide/reg...
Usually on registrars I feel like i'm digging to find something or figure out how to do something, Name.com makes it always feel like a click or two away somehow.
The only con is that they are based in France, so if you are in the United States, and use a credit card, you could get declined transactions due to fraud protection.