Kind of curious why the suggested way of installing is directly into the root python install. I figured it would have some sort of guide using virtualenv. I did see a requirements.txt in the repo, so I tried installing it in a virtual environment myself but had some issues compiling some modules (Tried both 2.7 and 3.4). I gave up at that point because it was more trouble than it was worth.
I really like the idea of this wiki as well as the look of it. I could definitely see myself using this in the future. I had spent some time a couple months ago looking into what Flask-based wikis were available but my results turned up very little. I'll definitely be watching this repo as it grows.