Criticizing Isotretinoin can only come from someone who doesn't understand what big of a deal acne can be. That drug saves millions of human lives from suicide.
I'm not saying severe acne or associated scaring can't cause mental health issues, but the list of side effects includes suicidal ideation, suicide, birth defects (it's a teratogen), depression (notably at the rate of between one in 1k and one in 10k), etc. This list [1] is quite extensive, and I'm glad I didn't have to sit on the fda council that decided this list of side effects was ok in a drug that, after all, just prevents some cosmetic scaring.