Modified yeast makes opiates for the first time
newscientist.com
newscientist.com
And the supporting info (implementation details) is here: https://pdf.yt/d/RF2kjrNT9gBhqCYw
Looks easy and fun! Seriously, Smolke's group did all the hard work; now, making your own codeine in yeast is $several thousand + the cost of GeneArt/IDT's DNA synthesis... and when you have the plasmids it's trivial to copy/modify/share them...