(Companies often reject profit-improving innovations which empower skilled workers. On the flipside, unions — to the extent they exist — also have the incentive to reject improvements which damage bargaining power. That's one problem with capitalism's built in boss/worker antagonism.)
Another is mind-numbing work. Adam Smith rants about how division of labor makes people "stupid and ignorant as it is possible for a human creature to become... But in every improved and civilised society this is the state into which the labouring poor, that is, the great body of the people, must necessarily fall, unless government takes some pains to prevent it." (http://www.econlib.org/library/Smith/smWN20.html#V.1.178)
Another (since the last century) is the rise of managerialism, with its bureaucracies. David Noble points out that tech can deskill workers and strengthen management, or empower workers and peel away management layers.