Give it to someone who had demonstrated ability to turn money into positive charitable outcomes, in preference to giving it to the government or typical NGOs, who mostly have demonstrated ability to turn it into sinecures. Better yet, give it to many such someones in parallel, because portfolio theory exists.
Continue maximizing on my comparative advantage in wealth generation as opposed to being comparatively ineffective but personally involved with charity, for the purpose of impressing people in cocktail conversation. Charity is, like heart surgery for my children, something I value highly enough to leave to very expensive dedicated professionals.