This is something so few people understand. And even if they did, they would still have to appreciate the thermodynamics and the non-linearity of the systems involved.

Medicine typically only knocks on the door with extracellular signaling. The cell remains a black box. Even if it weren't, with cancer we'd have to select certain cell populations based on internal cues that may never be exposed. Then there's the structure and pharmacology problems--there's a lot of chemistry and calculus along the path from drug introduction.