1. You're running a ton of tests, yet I see no mention of how you're adjusting your tests to account for multiple testing. The more tests you run the higher the chance you have of getting a false positive. Couple this with the majority of things you test probably won't be significantly better, and your chance of encountering a false positive is much much higher than you might think. You're running hundreds of tests and using a p-value of 0.05, but your chances of a false positive in your tests is much much much higher than 5%. Beware multiple tests and especially beware of the base rate fallacy.
2. Your post has no mention of statistical power or the size of the effect you're looking to detect. That makes me think you might not have considered this. If you don't know the effect size you're looking for or your statistical power, your A/B test results can't be trusted -- as you have no idea what your chances are of actually detecting a beneficial result if it exists.