Ask HN: Some Job-Seeking advice

TL;DR: How can I get a job at a Ruby/Node/Python/etc shop if I haven't worked in one already?

Hello HN,

I see all thee job postings for these really interesting companies that I'd love to work for. I even have some domain experience regarding their products, but I have only had one job before and that was a Java shop. So I have no professional experience in the stacks being used in most of these companies. I consider myself a fairly good programmer and I know I can pick up technologies fast enough. So do you think I am still eligible for these jobs? Advice on how I should approach these opportunities?

Full disclosure: I am nearly 23, have over an year of professional experience working on Enterprise level software for insurance companies in the middle east.