What profit or economics will drive colonization?
Consumption goods, not investment goods.
How do you convince ~100k people to pay 500k each to go there?
Back of the envelope Drake-like equation:
• Minimum wealth of richest 1% of Americans: $8.4 million
• Of those, 1% are in good enough mental and physical health to go
• Of those, 1% actually want to go.
That's 30,000 people. Obviously those numbers are seat-of-my-pants. Maybe only 1-in-a-thousand of people capable of making the trip want to go.
EDIT Tomp is right, my math was wrong.