It is hard to overstate how critical this fact is to Email's future. If you look at most of the canonical Internet protocols (SMTP, HTTP, DNS, XMPP, IRC, even BitCoin) - they have this fundamental feature in common. Even though they're part of the application layer of the Internet, they've become fundamental protocols that other technologies rely on. They are part of the infrastructure of the Internet.
I say this is someone who just started using Slack and loves it. I still can't see it replacing email, though.