Sugar and fructose cause heart disease (not fat) by irritating the lining of the heart over and over and over again. Wheat causes inflammation because most people are allergic to it in some way. Constant insulin response that we have with all the sugar hidden (and not so hidden) in everything we eat causes swelling and fat storage. Even the fruits we have now have been bred to be much much sweeter than 60 years ago.
Lets not even start on how fibre seems to protect against some of the terrible effects of fructose on the body (rapid conversion to fat - the body can't tolerate fructose in the blood) and how removing the fibre in the form of fruit juice or high fructose corn syrup is a disaster for your body.
Probably taking aspirin is unnecessary if you were to avoid the main things which irritate and cause an immune response in your body. I can bet you that turmeric tea from the root is going to be as good as aspirin at protecting you from these diseases but the best plan is to avoid sugar, wheat and high GI carbohydrates.